Developing neuroscience-based treatments for alcohol addiction: A matter of choice? Translational Psychiatry

science and alcohol

But today, alternative activities like wellness retreats, sober-friendly events and even dry bars are becoming increasingly popular. Many young people today see drinking as counterproductive to their mental health goals. They’re not afraid of challenging the old “let loose” mentality if it means staying sharp and feeling good.

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  1. More resources for a variety of healthcare professionals can be found in the Additional Links for Patient Care.
  2. However, only a minority of people transition from recreational to addictive alcohol use, a pattern that is similar to that of other addictions126,127.
  3. Drinking before bedtime can also fragment your REM sleep, and boost your risk for sleep apnea and alcohol addiction.

The failure so far to achieve more than at best marginal gains in alcoholism treatment through pharmacotherapy strongly suggest that business as usual in alcoholism research should not be considered an acceptable option. How drinking affects heart health may depend on the amount of alcohol consumed, though the evidence is far from conclusive. Some studies indicate that low-to-moderate drinking may actually lower your risk of heart disease and stroke, according to a 2021 review published in the journal Nutrients.

These platforms provide spaces for sharing alcohol’s risks while celebrating alternatives. Mental health awareness has also played an important role in magnifying this shift. Gen Z experiences higher rates of anxiety and depression than prior generations.

Scientists are finding that even moderate drinking may be more harmful than we thought—and certain groups are more at risk. Fizzy alcohol will make you feel the effects of alcohol more quickly as the bubbles increase the pressure in your stomach, forcing alcohol into your bloodstream faster. This is because when you eat the combined alcohol and food stays longer in the stomach. When it comes to alcohol, if you don’t drink, don’t start for health reasons. In the United States, people younger than age 21 are not legally able to drink alcohol. During pregnancy, drinking may cause the unborn baby to have brain damage and other problems.

For instance, a recent study in rats indicated that a history of alcohol dependence alters the functional connectivity of the anterior insula124. Chemogenetically silencing this structure using a DREADD (designer receptor exclusively activated by designer drug) changed alcohol’s interoceptive properties and approach behavior to the drug125. We believe that circuits-based manipulations need to be combined with functional neuroimaging both in animals and humans to better understand the effects of local interferences on large-scale brain network properties. With growing awareness of alcohol’s health risks, a “sober curious” movement has recently taken off, especially among millennials and young adults. Supporters advocate for a mindful approach to drinking, often encouraging periodic pauses like “Dry January” or “Sober October” and less alcohol consumption overall.

In any case, methanol poisoning is an emergency and should be treated immediately. Platforms like Instagram and TikTok have amplified this dialogue, with advocates openly discussing their sobriety journeys. By doing so, they further normalize prioritizing mental health over traditional drinking habits.

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But the exact effects will depend on the amount of alcohol consumed and how frequently someone drinks it. The products of methanol breakdown affect many other parts of the body too, resulting in a whole host of symptoms including vomiting, headache, visual disturbances that can include partial or total loss of vision, and difficulty breathing. In severe cases, methanol poisoning can cause convulsions, coma, and, after stopping breathing completely, death. Across the Atlantic, a United Kingdom report found that consumers aged 20 to 24 are nearly half as likely to prioritize spending on alcoholic beverages for home consumption compared to those aged 75 and older. “The liver has an enormous regenerative capacity,” says Paul Thomes, a researcher at Auburn University, whose work focuses on the mechanism of alcohol-induced organ damage. Of the four stages of alcohol-related liver disease, the first three can be reversed simply by not drinking.

It really does get harder to drink as you age

Despite these advances, we still do not fully understand why some people develop an addiction to drugs or how drugs change the brain to foster compulsive drug use. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Perhaps the two best-known alcohols are ethanol and methanol (or methyl alcohol). Ethanol is used in toiletries, pharmaceuticals, and fuels, and it is used to sterilize hospital instruments.

The bottom line is that alcohol is potentially addictive, can cause intoxication, and contributes to health problems and preventable deaths. If you already drink at low levels and continue to drink, risks for these issues appear to be low. As anyone who’s consumed alcohol knows, ethanol can directly influence brain function. Ethanol is classified as a “depressant” because it has a generally slowing effect on brain activity through activation of γ-aminobutyric acid (GABA) pathways. The consequences of drug use are vast and varied and affect people of all ages.

science and alcohol

When scientists began to study addictive behavior in the 1930s, people with an addiction were thought to be morally flawed and lacking in willpower. Those views shaped society’s responses to drug use, treating it as a moral failing rather than a health problem, which led to an emphasis on punishment rather than prevention and treatment. Depending on who you ask, you might be told to drink a few glasses of red wine a day or to avoid alcohol altogether. The reasons for such recommendations are many, but, by and large, they tend to stem from a study someone read about or saw reported in the news.

Methanol is used as a solvent, as a raw material for the manufacture of formaldehyde and special resins, in special fuels, in antifreeze, and for cleaning metals. Thus was ushered in humankind’s first biotechnology, based on empirical observation—with the help of fetal alcohol syndrome famous a microscopic organism, the yeast Saccharomyces cerevisiae (still used in modern fermented-beverage making). Lacking the means to preserve fruit and other natural products in season, people likely used fermentation as a way to increase the shelf life of food and drink. Together, medication and behavioral health treatments can facilitate functional brain recovery.